Study: Cannabidiol Reduces Brain Function Abnormalities in Psychosis

New research shows cannabidiol (CBD) may help readjust brain activity to alleviate abnormal functions, underscoring its potential therapeutic effect for psychosis, according to a study published in JAMA Psychiatry.

CBD, a non-intoxicating compound found in cannabis, has been investigated in several therapeutic areas. Although evidence supports CBD’s beneficial effects for psychotic disorders, the exact brain mechanisms that underlie its antipsychotic properties have remained unknown. The study findings provide insight into how CBD acts in the brain to reduce psychotic symptoms, which could pave the way for future developments in anti-psychotic treatments, according to the authors.

In the study, the researchers analyzed a group of 33 young individuals who had not been diagnosed with psychosis but were experiencing distressing psychosis symptoms, along with 19 healthy individuals in the control group. Data were collected from July 2013 to October 2016 and analyzed from November 2016 to October 2017.

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